(information for patients)
on medical administration of medicinal preparation
ZINC SULPHATE 0.25% AND BORIC ACID 2%
International non-proprietary name: None.
Drug formulation: solution (eye drops).
Description: transparent colorless or slightly yellowish liquid.
Composition: 1 ml of solution contains: zinc sulphate heptahydrate – 2.5 mg, boric acid – 20 mg; water for injection.
Pharmacotherapeutic group. Antimicrobial agents for treating diseases of eyes.
ATC Code: S01AX.
For treating blepharitis, conjunctivitis, preventing bacterial infections when a foreign body has penetrated into the conjunctival cavity.
Mode of administration and dosage
1 – 2 drops 2 – 4 times a day into the conjunctiva of the damaged eye.
Recommendations when dropping tubes are used. Before the preparation instilling remove the protective cap from the dropping tube, cut the body neck membrane off avoiding the thread damaging. Turn the dropping tube body upside down and press the dropping tube body gently using it as a pipette. After the preparation administration according to the physician’s prescription or as it is specified in the instruction turn the dropping tube so that the thread was upside and screw the protective cap on.
Allergic reactions can develop. Persons hypersensitive to the preparation components can complain on irritation and eye pain. When such events have continued for more than three days a physician should be addressed.
Individual hypersensitivity to the preparation components, renal function disorders, infancy up to 2 years.
The preparation should prescribed with caution to children aged 2 years and older.
When the preparation has been administered in doses exceeding the therapeutic dose for a long time chronic intoxication symptoms (nausea, fever, local edema of tissues) can appear. In such a case the preparation should be withdrawn.
Major symptoms of intoxication with boric acid: abdominal pain, diarrhea, nausea, erhythematous eruptions on the skin and mucous membranes, suppression or stimulation of the central nervous system functions, hyperthermia, convulsions, impairment of renal tubules.
When clinical effect is absent after the preparation has been administered for several days a physician should be addressed.
Administration during pregnancy and period of lactation
The boric acid administration is not indicated for breast feeding mothers for treating their mammary glands as well as for pregnant women.
Measures of precaution
Boric acid is absorbed via the gastrointestinal tract, damaged skin, wounds, and mucous membranes not penetrating markedly via the intact skin.
The boric acid preparations should not be applied on large surfaces of the body.
Impact on driving capacity and managing other potentially hazardous mechanisms
As eyes can become irritated when the preparation is administered one should be careful while driving and managing other mechanisms.
Interaction with other medicinal agents
It is pharmaceutically incompatible with other medicinal agents.
1 ml dropping tubes. 2 dropping tubes with an instruction on administration are put into a pack.
Keep at temperature not exceeding 25°C. Keep away from children.
Keep an opened dropping tube at temperature not exceeding 25°C for 2 weeks.
Terms of sale
Over the counter.
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