Sodium sulfacyl (solution 30% (eye drops))

Solution Sulfacyli natrii 30% (guttae ophthalmicae)


International nonproprietary name


Pharmacotherapy group

Antimicrobial preparation, sulfacetamide.


1 ml of solution contains 300 mg of sulfacetamide.

Pharmacological action


Sodium sulfacуl is a sulfonamide antimicrobial preparation of a wide range of action. It has a bacteriostatic effect. The mechanism of action is connected with competent antagonism to PABA and inhibition of dehydropteroatsynthetase that leads to the impairment of synthesis of tetrahydrofolic acid necessary for purine and pyrimidine synthesis.

It is active in relation to gram-positive and gram-negative bacteria (comprising colon bacillus, streptococcus, gonococcus, pneumococcus), as well as clamydia, actinomycetes.


On local application it is penetrated into the eye tissues and fluids. It can penetrate into the systemic blood flow through the inflamed conjunctiva, though because of insignificant amount of the preparation the systemic effect is not determined.


The preparation is used on conjunctivitis, blepharitis, septic ulcers of the cornea and other eye infections.


The preparation is instilled into the conjunctival sac, adults 2--3 drops of the solution 3 times a day.


In patients with higher individual sensitivity to furosemide, thiazide diuretics, sulfonyl-urea or carbohydrase inhibitors higher sensitivity to sodium sulfacyl may develop.


Onapplicationofthepreparationlocalirritationofthetissues (burning, reddening, edema, colic, lacrimation) ispossible, aswellasallergicreactions.


Higher sensitivity to sulfanylamid preparations.


Special care shall be taken in patients with burdened allergic anamnesis.


Simultaneous use of novocaine and tetracaine reduces the bacteriostatic effect of sodium sulfacyl. Incompatibility of sodium sulfacyl with silver salt is observed when used simultaneously.


On marked side effects (burning, reddening, edema, colic, lacrimation) the preparation of lower concentration (20% sodium sulfacyl solution) shall be used.

Product form

30% sterile solution (eye drops). It is produced in vials 5 ml.